Jason Trennert, Chief Investment Strategist, Managing Partner, Strategas Research Partners LLC, discusses whether now is a good time to get in or whether trouble lies ahead.
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FRIDAY, Dec. 2 (HealthDay News) -- People who have been diagnosed with colon cancer have a poorer prognosis if they're obese or have type 2 diabetes, new research suggests.
Two new studies that looked at the impact that body-mass index (BMI) and a diagnosis of type 2 diabetes had on survival rates after a colon cancer diagnosis found that both factors influence whether or not someone survives colorectal cancer. In addition, both studies found that deaths from any cause, including heart disease, were also increased in those who were obese or had type 2 diabetes.
Results of the studies were published online in the Journal of Clinical Oncology.
"The message here is to avoid obesity and type 2 diabetes because they have negative health outcomes. We don't know for sure that losing weight or increasing physical activity will help, but we know they're good for trying to avoid other diseases, like cardiovascular disease, that can come up down the road," said Dr. Jeffrey Meyerhardt, author of an accompanying editorial in the same journal, and an associate professor of medicine at the Dana-Farber Cancer Institute and Harvard Medical School in Boston.
There are more than 1 million people who've survived a colon cancer diagnosis living in the United States, and mortality from colorectal cancer has gone down over the past two decades, according to background information in the studies.
And, while previous research has linked a higher BMI and type 2 diabetes to the development of colorectal cancer in the first place, it hasn't been clear how these factors influence the course of colorectal cancer once someone has been diagnosed.
The first study included 2,303 people involved in an ongoing study that began in 1992. Between that time and 2007, the study participants had been diagnosed with colorectal cancer. Follow-up continued through December 2008.
During the study, 851 people with colorectal cancer died. Of those, 380 died as a result of colorectal cancer, while 153 died of heart disease, according to the study. The remaining 318 people died of other causes.
The risk of all-cause mortality was 30 percent higher for people who were considered obese at the start of the study vs. those of a normal weight. The risk of dying from colorectal cancer was 35 percent higher, and the risk of dying from heart disease was 68 percent higher.
Meyerhardt explained that the researchers tried to adjust the data for important factors, such as physical activity, red meat intake (a known risk factor for colorectal cancer), family history and blood pressure levels. Even after adjusting the data, obesity increased the risk of dying.
"In and of itself, obesity does seem to have some effect," Meyerhardt said.
In the second study, researchers recruited 2,278 people who'd been diagnosed with non-metastatic colon or rectal cancer between 1992 and 2007. In this group, there were 842 deaths. Of those, 377 were from colorectal cancer and 152 were from heart disease, according to the study.
People with type 2 diabetes had a 53 percent higher risk of dying from any cause and a 29 percent higher risk of dying from colorectal cancer compared to people without type 2 diabetes. The risk of dying from heart disease was 2.16 times higher in people with type 2 diabetes and nearly four times higher in people with type 2 diabetes who used insulin, compared with people without type 2 diabetes, the study found.
"Insulin use in type 2 diabetes usually indicates longer-standing diabetes, which is usually associated with worse outcomes," Meyerhardt noted.
Obesity, elevated body-mass index and diabetes are associated with worse disease states across the board," said Dr. David Bernstein, chief of gastroenterology at North Shore University Hospital in Manhasset, N.Y. "But, we don't know if you lose weight if that risk will go down. I don't counsel patients who've been diagnosed with colorectal cancer to lose weight, because weight loss tends to be a worry in people undergoing cancer treatment anyway. I do counsel my patients that haven't been diagnosed with cancer to lose weight. The medical community needs to spend more time counseling prevention."
Meyerhardt added that it's also not clear from these studies whether or not obese people or those with type 2 diabetes would benefit from changes in the treatment they receive for colorectal cancer.
More information
Learn more about preventing colorectal cancer from the American Cancer Society.
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Europe Finds ?1.3 Billion Needed for ITER Overruns
Source: Science
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Friday, Dec 02, 2011, 8:44am
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Source: http://www.labspaces.net/115660/Europe_Finds________Billion_Needed_for_ITER_Overruns
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TOKYO ? Public support for Japan's prime minister and his Cabinet has fallen 2.5 percentage points over the last month, as the administration's numbers continue to decline, a poll released Sunday shows.
Public approval for Prime Minister Yoshihiko Noda and his Cabinet stood at 44.6 percent in the Kyodo News agency poll. The administration's disapproval rating rose 6 points, to 40.3 percent.
Support for Noda has steadily declined since he took office in early September.
New prime ministers in Japan typically begin with relatively robust approval ratings, only to see them drop steadily after a brief honeymoon period. Noda is Japan's sixth prime minister in five years and faces a public frustrated with disaster reconstruction efforts and a lackluster economy.
Verbal gaffes have also hurt the Cabinet's image.
Noda's first trade minister resigned just eight days into the job after making comments seen as insensitive to nuclear crisis evacuees. Now Defense Minister Yasuo Ichikawa's days could be numbered as well.
Ichikawa is under fire for remarks made by his ministry's top official in Okinawa, where plans to relocate a U.S. Marine air base face strong opposition. The official, who has been dismissed, reportedly likened the move to rape, implying that the government would force its way onto the island.
The resulting outcry further intensified after Ichikawa told parliament that he was unfamiliar with details about the 1995 rape of an Okinawan schoolgirl by three U.S. servicemen. The incident fueled anti-American sentiment and concerns over U.S. military presence.
The opposition Liberal Democratic Party plans to submit a censure motion again Ichikawa on Friday.
Among other topics, respondents in the poll expressed wariness over the government's plans to raise the 5 percent consumption tax. More than half of those surveyed said they wanted a general election before a hike is enacted.
More than 71 percent said they wanted a realignment of political parties. The high figure suggests voters are unhappy with the status quo of two big political parties and several minor parties.
Kyodo randomly surveyed 1,021 eligible voters by telephone over the weekend. A poll of that size would typically have a margin of error of 5 percentage points.
The sample did not include areas in northeastern Fukushima prefecture that were evacuated because of the nuclear crisis spawned by the massive earthquake and tsunami last March.
___
Follow Tomoko A. Hosaka on Twitter at http://twitter.com/tomokohosaka
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Back when we first wrote about Vayable (the site that lets just about anyone offer to host paid tours/activities for travelers) Alexia said it was "like an Airbnb for Travel Experiences." Airbnb would agree, it seems. We've learned tonight that Airbnb is prepping to launch a partnership to upsell travelers with Vayable's tour experiences.Source: http://feedproxy.google.com/~r/Techcrunch/~3/UDHSEYx1kQQ/
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BERLIN (Reuters) ? Every country in the euro zone needs to set up a special national fund for sovereign debt that is more than 60 percent of gross domestic product, Germany's finance minister told a newspaper.
Wolfgang Schaeuble, detailing a proposal he will make at a European Union summit on December 9, told the Passauer Neue Presse that a total of 500 billion euros ($672 billion) would need to go into the German fund.
"We need a redemption fund in every single country of the euro zone," he told the newspaper in comments released on Saturday.
Tax revenues should be used to support the funds, Schaeuble said, adding that Germany would not need to raise taxes to implement the plan.
"Around 500 billion euros needs to be stored in the fund. This affects federal, state and municipal debt," he said.
German Chancellor Angela Merkel believes Schaeuble's proposal could help restore confidence in the euro, her spokesman said on Friday.
"The chancellor welcomes the proposal of introducing national redemption funds as very interesting," Steffen Seibert told a news conference.
Merkel has ruled out the idea of common euro zone debt issuance as a way to restore confidence in the currency bloc and Schaeuble again underlined Germany's opposition in the newspaper interview.
"There cannot be euro bonds. The German economy would be overburdened should we have to guarantee the debts of all the states. On top of this, the necessary pressure on countries to sort out their national debt problems would fall by the wayside.
If all were to keep to the stability criteria, then the problem is solved by itself."
Asked whether the European Central Bank's recent bond buying activities could increase inflation risks, Schaeuble said there was no reason to fear this.
"Serious economists see neither risk nor signs of inflation dangers. The euro is stable, inside and out."
He also rejected the idea of kicking Greece out of the euro zone as a way to help end the crisis.
"We can't just show states the door if they have difficulties. Also, the economic consequences would be totally unforeseeable were one or more countries to leave the euro zone. The vast majority say that this would be the worst of all developments."
($1 = 0.7446 euros)
(Reporting by Sylvia Westall, Editing by Chizu Nomiyama)
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NEW YORK (Reuters) ? Despite a budget crunch, New York City might have to increase funding for programs to help AIDS patients as its cost-cutting efforts have floundered and the state or federal governments could slice spending, a new report said on Tuesday.
New York City has one of the nation's largest populations of people living with AIDS -- 66,398 patients in 2009, the most recent data available.
The increase in this population has slowed from its 1990s spike to an average of about 1,669 new patients a year, according to the report by the Independent Budget Office. But the city has little control over the number of patients because doctors determine whether someone has AIDS.
Further, the city's cash crunch is far from unique.
New York State faces future deficits that run in the multibillions of dollars while the federal government is struggling to cut its own deficit.
The city will contribute about half of the total of $225 million earmarked for assisting AIDS patients with housing, health and homemaker services, and the like in the current budget, the report said.
Mayor Michael Bloomberg, a political independent, has failed repeatedly to curb the costs of caring for AIDS patients. Legal requirements Bloomberg could not overturn set the number of caseload managers, and the City Council, led by Democrats, repeatedly restored his cuts, the report said.
AIDS patients, who lived an average of just over 109 months in 2008, also get the benefit of other public assistance, such as Medicaid, the federal-state plan for the poor, elderly and disabled, and the federal food stamp program, for example.
In November, Bloomberg did not propose any new cuts for the HIV/AIDS programs, the report said.
"This may reflect that the city's efforts to find savings in the HIV/AIDS Services Administration are not likely to get any easier in the future," it added.
SOURCE: http://bit.ly/t7KYPm Independent Budget Office, November 29, 2011.
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